Drips marketed as Athletic IV, Performance IV, Energy & Performance IV, or Brain Boost IV—typically B vitamins, amino acids, and fluids, sometimes stacked with NAD+. Useful as elective nutrient delivery around training or travel; not a proven ergogenic drug or nootropic, and athletes should check anti-doping rules.
IV therapy for energy and performance covers Athletic IV, Performance IV, Energy & Performance IV, and Brain Boost IV menus. Formulas usually combine fluids, B-complex (energy-metabolism cofactors), magnesium, and amino acids such as taurine; some clinics add NAD+ or extra vitamin C. The pitch is faster recovery, sharper focus, or a better session. The evidence bar for those outcomes in already-nourished adults is low.
What Might Be in the Bag
B vitamins: cofactors in mitochondrial ATP pathways. They treat deficiency (including some neuropathies and true B12 deficiency), not a guaranteed “energy surge” when stores are full.
Fluids and electrolytes: help when sweat losses are high. They do not increase VO2 max by themselves.
Brain Boost add-ons: often more B vitamins, magnesium, or amino acids. These are not approved nootropics. NAD+ IVs, if used, are a separate, slower infusion with their own evidence limits.
Athletes
IV infusions of more than 100 mL per 12 hours can violate World Anti-Doping Agency rules except in legitimate medical treatment. Competitive athletes should not use a performance drip as a loophole. Recreational trainees can still use oral nutrition, which is first-line.
Summary
Energy and performance IVs are nutrient and fluid bags with a sports label. Training, sleep, carbohydrate, and iron status move performance more than a drip. Get the ingredient list and skip it if you are in a tested sport without medical indication.
Eat and hydrate. Tell staff if you are in a tested sport. Bring labs if fatigue is chronic (iron, B12, thyroid). Disclose stimulants and NAD+ history.
Normal activity the same day for a standard bag. NAD+ may leave you tired the same afternoon. Performance the next session still depends on fueling.
Vein irritation, flushing, fluid overload, G6PD risk if high-dose vitamin C is stacked, and anti-doping violations for IV volume in tested athletes. Not FDA-approved as an ergogenic aid or nootropic.
World Anti-Doping Agency. Prohibited List (IV infusions).
https://www.wada-ama.org/en/prohibited-listSawka M.N. et al. ACSM Position Stand: Exercise and Fluid Replacement (Med Sci Sports Exerc, 2007).
https://doi.org/10.1249/mss.0b013e31802ca597CDC. Injection Safety and Safe Practices (One & Only Campaign).
https://www.cdc.gov/injection-safety/USP <797> Sterile Compounding Standards (overview).
https://www.usp.org/compounding/usp-compounding-standards© 2026 Longevity Clinic Finder. All rights reserved.
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Frequency
Occasional use around events or travel is more defensible than a standing weekly “brain boost” in healthy, replete adults.
Recreational athletes and travelers who want labeled nutrients and understand claims are soft. Tested athletes need medical indication and anti-doping advice. Not a workup replacement for unexplained fatigue.
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